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CXCR2 — IRF6

Text-mined interactions from Literome

Juffermans et al., J Infect Dis 2000 (Endotoxemia...) : In healthy subjects, LPS induced a transient decrease in granulocyte CXCR1 and CXCR2 expression, whereas in tuberculosis patients, only CXCR2 showed reduced levels ... In whole blood in vitro, LPS , lipoarabinomannan from Mycobacterium tuberculosis, and lipoteichoic acid from Staphylococcus aureus reduced expression of CXCR2 but not of CXCR1 ... CXCR2 down-regulation induced by LPS or tumor necrosis factor-alpha in vitro was abrogated by a p38 mitogen activated protein kinase ( MAPK ) inhibitor
Tikhonov et al., Clin Exp Immunol 2001 : In contrast, LPS reduced CXCR1 and CXCR2 expression in purified PMN and whole blood in a TNF-alpha independent manner
Reutershan et al., J Clin Invest 2006 : The LPS induced increase in lung microvascular permeability as measured by Evans blue extravasation required CXCR2 on nonhematopoietic cells
Khandaker et al., J Immunol 1998 : In the present study, we investigated the mechanism by which bacterial LPS induces the down-modulation of IL-8 responsiveness and CXCR1 and CXCR2 expression on human neutrophils