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EPHB2 — MUC1

Text-mined interactions from Literome

Meerzaman et al., Am J Physiol Lung Cell Mol Physiol 2001 : Involvement of the MAP kinase ERK2 in MUC1 mucin signaling
Kim et al., J Korean Med Sci 2002 (MAP Kinase Signaling System) : PD98059 ( MEK/ERK inhibitor ) suppressed IL-1beta mediated MUC2 gene expression and mucin secretion, while SB203580 ( p38 inhibitor ) did not
Alcaide et al., Eur J Immunol 2004 (Chagas Disease) : Furthermore, AgC10 inhibition must lie upstream in the MAPK activation pathway by LPS, since this mucin also inhibited extracellularly regulated kinase (ERK) and Jun kinase (JNK)activation
Lillehoj et al., Am J Physiol Lung Cell Mol Physiol 2004 : Our results showed 1 ) the Muc1 CT was phosphorylated constitutively on serine and tyrosine, 2 ) serine phosphorylation was stimulated by bacterial cells or flagellin, and 3 ) binding of P. aeruginosa or flagellin to Muc1 induced phosphorylation of ERK
Koga et al., Am J Physiol Lung Cell Mol Physiol 2007 : Both U0126, an inhibitor of MEK1/2, and dominant negative ERK1 prevented TNF-alpha induced MUC1 promoter activation, and anti-TNFR1 antibody blocked TNF-alpha stimulated ERK1/2 activation
Lim et al., American journal of translational research 2009 : In the present study, we showed that positive regulation of MUC5AC mucin expression by ERK1/2 is dependent on Ras-Raf-1 signaling pathway, whereas the negative regulation of MUC5AC expression by JNK1/2 is dependent on MEKK3 ... Ras-Raf1-ERK1/2 dependent AP-1 activation positively regulates MUC5AC mucin induction by S. pneumoniae, whereas MEKK3-JNK1/2 dependent AP-1 activation negatively regulates it
Xu et al., PloS one 2012 : Suppression of MUC1 expression resulted in EGFR destabilization and inhibition of the BPDE induced activation of Akt and ERK and increase of cytotoxicity