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KRT1 — KRT18
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
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Gene Ontology Complexes intermediate filament:
intermediate filament complex (KRT39-KRT38-KRTAP4-2-KRT31-NME1-NME2-KRT32-KRT35-KRT34-KRT37-KRT36-KRT222-KRTAP4-6-KRTAP3-1-MICAL1-KRTAP1-1-KRT28-KRTAP1-3-KRTAP1-4-KRTAP1-5-KRT23-KRT20-KRT26-KRT27-KRT24-KRT25-LMNTD1-KRTAP21-3-KRTAP27-1-KRTAP20-2-KRTAP20-3-KRTAP20-1-KRTAP20-4-KRTAP10-8-KRTAP6-2-KRTAP10-5-KRTAP10-4-KRTAP10-3-KRTAP10-2-KRTAP10-1-VIM-KRTAP23-1-KRTAP25-1-SYNM-DES-SYNC-PRPH-FLG-KRTAP4-9-KRTAP9-9-KRTAP7-1-KRTAP9-1-KRTAP9-2-KRTAP9-3-KRTAP9-4-KRTAP4-4-KRTAP9-6-KRTAP9-7-JUP-KRT40-KRTAP10-12-DSP-KRTAP10-10-KRTAP12-1-GJA1-KRTAP12-3-KRTAP12-2-KRTAP12-4-KRTAP24-1-KRT17-KRT16-KRT15-KRT14-KRT12-KRT10-INA-KRT19-KRT18-KRT75-KRT74-KRT77-KRT76-KRT71-KRT73-KRT72-KRT79-KRT78-KRT3-KRT2-KRT1-KRT7-KRT4-KRT9-KRT8-NES-KRTAP5-10-KRT80-KRT81-KRT82-KRT83-KRT84-KRT85-KRT86-KRTAP19-2-KRTAP19-3-KRTAP19-1-KRT6B-KRT6C-KRTAP19-4-KRT6A-KRTAP19-6-KRTAP19-8-KRTAP19-7-KRTAP5-4-LMNB2-KRTAP5-6-KRTAP5-7-KRTAP5-1-KRTAP5-2-KRTAP5-3-KRTAP2-3-KRTAP2-1-KRTAP19-5-KRTAP5-9-KRTAP15-1-LMNB1-KRTAP4-16P-KRTAP2-4-KRTAP16-1-KRTAP21-2-KRTAP21-1-KRTAP11-1-KRTAP22-1-KRTAP22-2-KRTAP5-5-EIF6-KRTAP4-5-KRTAP8-1-KRTAP29-1-NCKIPSD-KRT87P-NEFL-KRT33A-KRTAP6-3-NEFH-KRTAP6-1-CLIP1-KRTAP17-1-GFAP-KRTAP4-8-KRTAP3-2-BFSP2-MNS1-BFSP1-KRTAP13-4-KRTAP13-1-KRTAP13-2-KRTAP13-3-KRTAP4-11-LMNA-KRTAP4-12-KRTAP26-1-KRTAP3-3-NEFM-KRT33B-SLC1A4-KRTAP4-3)
de Bernard et al., EMBO J 2000, Hofmann et al., J Cell Sci 2000, Suzuki et al., J Biol Chem 2002, Collin et al., Differentiation 1992, Collin et al., Exp Cell Res 1992, Bilbe et al., EMBO J 1992, Yang et al., Circ Res 2006, Langbein et al., J Biol Chem 2010, Glass et al., J Cell Biol 1985, Leube et al., J Cell Biol 1988, Zhou et al., J Biol Chem 1988, McKinley-Grant et al., Proc Natl Acad Sci U S A 1989, Moll et al., Differentiation 1993, Ku et al., J Biol Chem 1997, Irvine et al., Nat Genet 1997, Winter et al., J Biol Chem 1997, Hess et al., Exp Eye Res 1998, Muñoz-Mármol et al., Proc Natl Acad Sci U S A 1998, Yaworsky et al., Dev Biol 1999
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IRef Hprd Interaction:
Complex of 1567 proteins
(in vivo)
Catimel et al., J Proteome Res 2005
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IRef Hprd Interaction:
Complex of 57 proteins
(in vivo)
Catimel et al., J Proteome Res 2005
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IRef Intact Interaction:
Complex of 185 proteins
(association, cross-linking study)
Humphries et al., Science signaling 2009
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IRef Intact Interaction:
Complex of 177 proteins
(association, cross-linking study)
Byron et al., Proteomics 2012
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IRef Intact Interaction:
Complex of 168 proteins
(association, cross-linking study)
Byron et al., Proteomics 2012
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IRef Intact Interaction:
Complex of 400 proteins
(association, cross-linking study)
Humphries et al., Science signaling 2009
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IRef Intact Interaction:
Complex of 203 proteins
(association, cross-linking study)
Byron et al., Proteomics 2012
Text-mined interactions from Literome
Ku et al., Hepatology 2003
(Liver Diseases) :
Both Fas- and TNF induced apoptosis in liver tissues are associated with caspase mediated
K18 degradation and
increased keratin phosphorylation on several but not all sites
Dlugosz et al., Cancer Res 1995
(Cell Transformation, Neoplastic...) :
Moreover, v-rasHa elicited characteristic changes in marker expression (
keratin 1 was suppressed
; keratin 8 was
induced ), previously shown to be associated with epidermal growth factor (EGF) receptor activation, in both TGF alpha +/+ and TGF alpha -/- keratinocytes