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ATP5O — TFP1

Text-mined interactions from Literome

Boland et al., Magn Reson Chem 2004 : The K ( D ) was much higher than the IC ( 50 ) for ATPase inhibition ( 8 microM ), which suggests that the substantial non-specific binding of TFP to the membranes contributes to ATPase inhibition
Souza dos Santos et al., Exp Brain Res 2007 : However, when 0.5-1 mM H2O2 is added together with Fe ( 2+ ) /ascorbate, both BHT and TFP only partially prevent ATPase activity inhibition, and DTT does not confer any protection, suggesting two possible additional mechanisms involving both lipid peroxidation and direct damage to PMCA at amino acid residues other than cysteines
Li et al., Zhongguo Yao Li Xue Bao 1991 (Stomach Ulcer) : TFP 20 mg.kg-1 ig inhibited the gastric H+, K ( + ) -ATPase activity of both stress and indomethacin ulcers in rats in vivo, and the gastric H+, K ( + ) -ATPase activity was also inhibited by TFP 50 mumol.L-1 in vitro
Maran et al., Biochem Med Metab Biol 1990 : The induction of t-PA-Ag biosynthesis by PtdIns liposomes in FLF was inhibited by 5-15 microM verapamil, an inhibitor of Ca2+ uptake via the so-called `` slow channels '' by 0.5-10 microM TFP , an inhibitor of Ca2+ transport ATPase , and by 10-90 microM TMB-8, an inhibitor of intracellular Ca2+ mobilization
Levy et al., Diabetes 1986 (Diabetes Mellitus, Experimental...) : The high-affinity Ca2+-Mg2+-ATPase activity was inhibited by trifluoroperazine (TFP) in both membranes
Eilam et al., J Gen Microbiol 1985 : Trifluoperazine (TFP) , the antipsychotic drug, induces substantial K+ efflux, membrane hyperpolarization and inhibition of H+-ATPase in the yeast Saccharomyces cerevisiae
Mrwa et al., Arzneimittelforschung 1980 : Trifluoperazine (TFP) inhibits superprecipitation and ATPase activity of smooth muscle actomyosin
García et al., J Bioenerg Biomembr 1995 : The effect of trifluoperazine (TFP) on the ATPase activity of soluble and particulate F1-ATPase and on ATP synthesis driven by succinate oxidation in submitochondrial particles from bovine heart was studied at pH 7.4 and 8.8