Gene interactions and pathways from curated databases and text-mining

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CFP — TNF

Text-mined interactions from Literome

Nakstad et al., Crit Care Med 2001 (Systemic Inflammatory Response Syndrome) : In the presence of high PFC concentrations, simulating the condition in which bronchoalveolar cells are exposed to PFC, monocytes may be induced by PFB to produce reactive oxygen species, and blood leukocytes induced by PFB to express CD11b and by PFD to secrete interleukin-8 ; the presence of either PFC attenuated tumor necrosis factor-alpha production after lipopolysaccharide stimulation
Wissel et al., Pediatr Res 2006 : Perfluorocarbons (PFC) are beneficial in animals with bacterial pneumonia and reduce production of TNF-alpha ... Using isolated ATII-cells, it was studied whether PFC prevent C. pneumoniae induced TNF-alpha and MIP-2 release and what the underlying pathway is