◀ Back to APOB
APOB — TFPI
Text-mined interactions from Literome
Horie et al., Biochem J 2000
:
It did not affect the mRNA level, but
ox-LDL dependent reduction of the
TFPI antigen level in HUVEC was reversed by the simultaneous treatment of ox-LDL with bafilomycin A1, an inhibitor of the lysosomal proton pump
Horie et al., Thromb Haemost 2002
:
These results indicate that the C-terminal domain of TFPI molecule plays a predominant role in the binding to ox-LDL and the binding through the C-terminal part is essential for the
ox-LDL dependent reduction of the anticoagulant activity of
TFPI
Li et al., Zhonghua Xin Xue Guan Bing Za Zhi 2006
:
To investigate the
effects of
ox-LDL , ACEI and ARB on expressions and activities of TF and
TFPI in VSMC ... ( 2 ) The
effects of
ox-LDL and valsartan on TF and
TFPI expressions were analyzed by immunohistochemistry and immunofluorescence
Rosenson et al., Atherosclerosis 1998
(Coronary Disease...) :
Conversely,
LDL inhibits
tissue factor pathway inhibitor (TFPI) which limits activation of the extrinsic coagulation pathway