Gene interactions and pathways from curated databases and text-mining

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CD36 — LEP

Text-mined interactions from Literome

Horiuchi et al., Ann N Y Acad Sci 2005 (Diabetic Nephropathies) : In this study, we focused on two AGE receptors-specifically, the role of SR-A in pathogenesis of diabetic nephropathy and the role of CD36 in AGE induced downregulation of leptin by adipocytes
Unno et al., Ann N Y Acad Sci 2005 (Metabolic Syndrome X) : These results indicate that the ligand interaction of GA-BSA with CD36 leads to downregulation of leptin expression in 3T3-L1 adipocytes, suggesting that AGE induced leptin downregulation is linked to reduction of the insulin sensitivity in metabolic syndrome
Rosales Nieto et al., Animal 2013 : Leptin concentration increased with increases in values for EMD ( P < 0.001 ), FAT ( P < 0.001 ), PWT ( P < 0.001 ), PEMD ( P < 0.05 ) and PFAT ( P < 0.05 )