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NFKB1 — TNIP1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: Complex of 11 proteins Bouwmeester et al., Nat Cell Biol 2004
• IRef Biogrid Interaction: NFKB1 — TNIP1 (physical association, affinity chromatography technology) Cohen et al., Biochem Biophys Res Commun 2009*
• IRef Biogrid Interaction: NFKB1 — TNIP1 (direct interaction, two hybrid) Wang et al., Molecular systems biology 2011
• MIPS CORUM CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 complex: CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 complex complex (CHUK-COPB2-IKBKG-NFKB1-NFKB2-NFKBIA-NFKBIE-REL-RELA-SPAG9-TNIP1-TNIP2) Bouwmeester et al., Nat Cell Biol 2004
• IRef Corum Interaction: Complex of 13 proteins (association, tandem affinity purification) Bouwmeester et al., Nat Cell Biol 2004
• IRef Dip Interaction: TNIP1 — NFKB1 (physical association, tandem affinity purification) Bouwmeester et al., Nat Cell Biol 2004
• IRef Hprd Interaction: Complex of 145 proteins (in vivo) Bouwmeester et al., Nat Cell Biol 2004
• IRef Intact Interaction: TNIP1 — NFKB1 (physical association, two hybrid) Wang et al., Molecular systems biology 2011
• IRef Ophid Interaction: TNIP1 — NFKB1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: TNIP1 — NFKB1 (aggregation, confirmational text mining) Bouwmeester et al., Nat Cell Biol 2004

Text-mined interactions from Literome

Mauro et al., J Biol Chem 2006 : We find that both ABIN-1 and A20 inhibit NF-kappaB at the level of the IKK complex and that A20 inhibits activation of NF-kappaB by de-ubiquitination of NEMO/IKKgamma
Verstrepen et al., Biochem Pharmacol 2009 : Similar to A20, ABIN-1 and ABIN-3 expression is NF-kappaB dependent , implicating a potential role for the A20/ABIN complex in the negative feedback regulation of NF-kappaB activation
Cohen et al., Biochem Biophys Res Commun 2009 : ABIN-1 negatively regulates NF-kappaB by inhibiting processing of the p105 precursor