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FGF2 — JAG1

Text-mined interactions from Literome

Saravanamuthu et al., Dev Biol 2009 (MAP Kinase Signaling System) : FGF induced Jag1 expression and Notch2 signaling ( as judged by the appearance of activated Notch2 Intracellular Domain (N2ICD) ) within 12-24 h ... Inhibition of Notch signaling using gamma secretase inhibitors DAPT and L-685,458 or anti-Jag1 antibody markedly decreased FGF dependent expression of Jag1 demonstrating Notch dependent lateral induction
Kiec-Wilk et al., J Physiol Pharmacol 2010 : The study analyzed the signalling pathways involved in the regulation of Jagged-1/Notch-4 expression in endothelial cells ( HUVECs ) in response to VEGF, bFGF and PPAR-gamma exogenous activator - ciglitazone ... The opposite effect of VEGF, bFGF , or ciglitazone on the Jagged-1/Notch-4 expression on HUVEC was connected with the different activation of MAPKs