Gene interactions and pathways from curated databases and text-mining

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HDAC1 — PI3

Text-mined interactions from Literome

Aoukaty et al., J Biol Chem 2002 (Lymphoproliferative Disorders) : We report here a role for phosphoinositide 3-kinase (PI3K) in the recruitment and association of SAP/SH2D1A to 2B4 in human NK cells
Shimizu-Hirota et al., Genes Dev 2012 : In turn, MT1-MMP dependent PI3Kd activation regulates the immunoregulatory Mi-2/NuRD nucleosome remodeling complex that is responsible for controlling macrophage immune response
Moskowitz et al., Curr Oncol Rep 2012 (Hodgkin Disease) : Additional agents that have demonstrated activity in HL include histone deacetylase inhibitors, such as panobinostat, entinostat, and mocetinostat, PI3-kinase/Akt/Mtor pathway inhibitors , such as everolimus, as well as lenalidomide and bendamustine