Kawakami et al., Proc Natl Acad Sci U S A 2000
:
Syk/Btk mediated PKCbetaI regulation is involved in transcriptional activation of the IL-2 and tumor necrosis factor alpha genes through the JNK pathway induced by FcepsilonRI stimulation
Hata et al., J Biol Chem 1998
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Collectively, these data demonstrate that Btk regulates the transcription of the IL-2 gene through the JNK-regulatable transcription factors in FcepsilonRI stimulated mast cells