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LYN — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: LYN — TP53 (physical association, affinity chromatography technology) Ren et al., Cancer Biol Ther 2002*

Text-mined interactions from Literome

Bezombes et al., Mol Pharmacol 2002 : We demonstrate that PKCzeta inhibited p53/p56 Lyn phosphorylation and stimulation in drug- or H ( 2 ) O ( 2 ) -treated cells, suggesting that p53/p56 Lyn redox regulation is altered in PKCzeta overexpressing cells
Ren et al., Cancer Biol Ther 2002 : Lyn increases p53 levels and stimulates p53 mediated transcription by a kinase independent mechanism ... The results also demonstrate that Lyn increases nuclear levels of ubiquitinated p53 by inhibiting export of p53 to the cytoplasm