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GRAP2 — PI3

Text-mined interactions from Literome

Pfundt et al., Arch Dermatol Res 2000 : SB202190 or SB203580, two specific p38 MAP kinase inhibitors almost completely blocked the induction of SKALP expression by TNF-alpha and serum
Yamamori et al., Biochem Biophys Res Commun 2002 : Phosphatidylinositol 3-kinase (PI3K) inhibitors, wortmannin and LY294002, blocked not only p38 MAPK activation but also Rac activation
Tchaikovski et al., Arterioscler Thromb Vasc Biol 2008 : PI-3K appears to be a central regulator in VEGFR-1 signaling in monocytes as the activation of Akt, p38 , and ERK1/2 are PI-3-K dependent
Lin et al., Rheumatol Int 2008 (Chondrosarcoma...) : Using chondrosarcoma cells stimulated with IL-1beta, the effects of GLN on the mRNA and protein levels of MMP-3, the activation of JNK, ERK, p38 , NF-kappaB, and AP-1, the nuclear translocation of NF-kappaB/Rel family members, and PI3-kinase/Akt activation were studied
Park et al., J Invest Dermatol 2008 (Keloid) : The level of Smad2/3, signal transducer and activator of transcription-3 ( STAT3 ), and p38 phosphorylation is more enhanced in KFs, and EGCG inhibited phosphorylation of phosphatidylinositol-3-kinase (PI3K) , extracellular signal regulated protein kinase 1/2 ( ERK1/2 ), and STAT3 ( Tyr705 and Ser727 )
Xu et al., Int J Mol Med 2013 : In another set of cultures, the cells were co-incubated with RTB and the tyrosine kinase inhibitor, genistein, the phosphatidylinositol 3-kinase (PI3K) inhibitor, LY294002, the p42/44 inhibitor, PD98059, the p38 inhibitor , SB203580, the JNK inhibitor, SP600125, the protein kinase C ( PKC ) inhibitor, staurosporine, the JAK2 inhibitor, tyrphostin ( AG490 ), or the NOS inhibitor, L-NMMA
Berra et al., J Biol Chem 1998 : Consistent with this, expression of active mutants of PI 3-kinase and Akt inhibits p38 activation and apoptosis