Gene interactions and pathways from curated databases and text-mining

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IFNA4 — IRF1

Text-mined interactions from Literome

Rubinstein et al., Antiviral Res 2000 : While interferon alpha A was more sensitive than interferon tau to the inhibitory effects of the IRF-2 DBD, IRF mediated gene induction is involved in successful interferon alpha and tau induced anti-VSV activity
Zhou et al., Ann Oncol 2000 (Carcinoid Tumor) : The interferon-alpha regulation of interferon regulatory factor 1 (IRF-1) and IRF-2 has therapeutic implications in carcinoid tumors
Barnes et al., J Biol Chem 2001 : Virus-specific activation of a novel interferon regulatory factor , IRF-5, results in the induction of distinct interferon alpha genes
Lin et al., Oncogene 2001 : vIRF-1 has been shown to downregulate the interferon- and IRF mediated transcriptional activation of ISG and murine IFNA4 gene promoters
Hahn et al., J Virol 2005 (Leukoplakia, Hairy) : However, IRF-7 dependent activity of the IFN-alpha4 , IFN-beta, and Tap-2 promoters, as well as an ISRE promoter construct, was inhibited by BZLF-1
Au et al., Nucleic Acids Res 1992 (Newcastle Disease) : In the present study, we have shown that the interferon regulatory factor 1 (IRF-1) can induce expression of both IFN-alpha 4 and -alpha 6 in a transient expression assay
Hochhaus et al., Leukemia 1997 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : Expression of interferon regulatory factor ( IRF ) genes and response to interferon-alpha in chronic myeloid leukaemia
Schafer et al., J Biol Chem 1998 : Surprisingly, activation of the IFNA4 gene promoter by virus and IRF-1 in these cells was inhibited by IRF-3