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MMP9 — PDGFB

Pathways - manually collected, often from reviews:

• WikiPathways Angiogenesis: PDGFB/MMP9/VEGFA/MMP2/ANGPT1/FGF2 → PDGFB (activation)
• WikiPathways Angiogenesis: PDGFB/MMP9/VEGFA/MMP2/ANGPT1/FGF2 → MMP2/MMP9 (activation)

Text-mined interactions from Literome

Karakiulakis et al., J Biol Chem 2007 (Anoxia) : PDGF-BB inhibited the synthesis and secretion of all hypoxia dependent MMP via Erk1/2 mitogen activated protein ( MAP ) kinase activation
Liu et al., Neurol Res 2008 (Disease Models, Animal...) : So, PDGF-B may induce the expression of MMP for the degradation of collagen type III on the wall of the saccular aneurysms
Kim et al., Cancer Lett 2012 (Breast Neoplasms) : In addition, EGF induced MMP-9 expression was inhibited by UO126 ( a MEK1/2 inhibitor ) or SIS3 ( a smad3 inhibitor ), but not by SP600125 ( a JNK inhibitor )
Alexander et al., Curr Eye Res 1998 : A phorbol mitogen ( TPA ), and TNF alpha and beta, interleukin-1 alpha and PDGF BB stimulate gelatinase B , stromelysin, interstitial collagenase and TIMP-1 expression, while having negligible effects on gelatinase A expression ; TIMP-2 levels are reduced by TNF but not affected by the other treatments