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AHSA1 — FAS

Text-mined interactions from Literome

Ivanov et al., Oncogene 2000 (Melanoma) : Inhibition of p38 activity also restored NF-kappaB activity and Fas expression in early-phase melanoma cells, suggesting that p38 elicited suppression of Fas expression is not restricted to late phase melanoma
Choi et al., J Neurooncol 2002 (Astrocytoma...) : Herein, we demonstrate that : ( 1 ) Among these cytokines, only IL-6 was induced upon Fas ligation in a dose- and time dependent manner ; ( 2 ) A selective p38 MAP kinase inhibitor, SB202190, and a MEK inhibitor, U0126, suppressed induction of IL-6 mRNA and protein expression by Fas ligation ; and ( 3 ) Glioblastoma multiforme samples ( n = 11 ) contain significantly higher levels of IL-6 compared to those of control brains ( n = 5 ), which correlate with increased levels of Fas
Juo et al., Mol Cell Biol 1997 : In this study, crmA antagonized, and YVAD-CMK and Z-VAD-FMK completely inhibited, Fas activation of p38 kinase activity, demonstrating that Fas dependent activation of p38 requires ICE/CED-3 family members and conversely that the MKK3/p38 activation cascade represents a downstream target for the ICE/CED-3 family proteases