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BCL2 — IL1B

Text-mined interactions from Literome

Kühn et al., J Immunol 2000 : In addition, IL-1 beta significantly increased the expression of Bcl-2
Marselli et al., J Clin Endocrinol Metab 2001 : IL-1beta , interferon gamma, and TNF alpha caused no major change in either islet cell survival or Bcl-2 and Bax mRNA expression after a 12-h incubation ; however, a marked increase in the amount of dead cells, with a major decrease of Bcl-2 mRNA expression, was observed after 72 h
Chandrasekar et al., J Biol Chem 2004 (Inflammation) : Treatment of HCMEC with IL-18 increases 1 ) NF-kappaB DNA binding activity ; 2 ) induces kappaB-driven luciferase activity ; 3 ) induces IL-1beta and TNF-alpha expression via NF-kappaB activation ; 4 ) inhibits antiapoptotic Bcl-2 and Bcl-X ( L ) ; 5 ) up-regulates proapoptotic Fas, Fas-L, and Bcl-X ( S ) expression ; 6 ) induces fas and Fas-L promoter activities via NF-kappaB activation ; 7 ) activates caspases-8, -3, -9, and BID ; 8 ) induces cytochrome c release into the cytoplasm ; 9 ) inhibits FLIP ; and 10 ) induces HCME cell death by apoptosis as seen by increased annexin V staining and increased levels of mono- and oligonucleosomal fragmented DNA
Cooke et al., Transplantation 2005 : Overexpression of human Bcl-2 in syngeneic rat donor lungs preserves posttransplant function and reduces intragraft caspase activity and interleukin-1beta production ... The authors investigated whether gene transfer of the human antiapoptotic protein Bcl-2 by means of intratracheal adenoviral administration would preserve posttransplant lung function and reduce intragraft activated caspase activity and IL-1beta production in syngeneic rat donor lung grafts
Lizard et al., FEBS Lett 1997 (Leukemia) : 7Beta-hydroxycholesterol and 7-ketocholesterol induced nuclear condensation and/or fragmentation, internucleosomal DNA fragmentation, and IL-1beta secretion, which were partially inhibited by Bcl-2 overexpression
Lee et al., Mol Genet Metab 1998 : Bcl-2 regulates nonapoptotic signal transduction : inhibition of c-Jun N-terminal kinase (JNK) activation by IL-1 beta and hydrogen peroxide