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CDK6 — SMAD3

Text-mined interactions from Literome

Ogasawara et al., Mol Cell Biol 2004 : Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad mediated down-regulation of Cdk6
Cheng et al., Chem Biol 2012 (MAP Kinase Signaling System) : We found that indirubin derivative E738 inhibited both TGFß and BMP pathways through ubiquitin-proteasome mediated depletion of total R-Smad pools, although phospho-R-Smad levels were initially stabilized by GSK3ß and cyclin dependent kinase inhibition