Gene interactions and pathways from curated databases and text-mining

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CNTF — SOAT1

Text-mined interactions from Literome

Schaefer et al., Cell Signal 2000 (Brain Neoplasms) : Interleukin-6, leukemia inhibitory factor, and ciliary neurotrophic factor also induced Stat complexes more selectively and to a lesser magnitude than oncostatin M
Peterson et al., J Neurosci 2000 : CNTF induced activation of Jak-STAT signaling prompted us to investigate STAT3 phosphorylation after a variety of stress mediated, conditioning stimuli
Zvonic et al., J Biol Chem 2003 : In order to investigate the effects of CNTF on fat cells, we examined the expression of CNTF receptor complex proteins ( LIFR, gp130, and CNTFRalpha ) during adipocyte differentiation and the effects of CNTF on STAT , Akt, and MAPK activation
Jiao et al., Brain Res Mol Brain Res 2003 (Neuroblastoma) : Expression of dominant negative forms of the tyrosine phosphatases, SHP-1 and/or SHP-2, in BE ( 2 ) -C cells had no effect on CNTF activation of STAT or on the ability of phosphatase inhibitors to block signaling
Kaur et al., J Neurochem 2005 : Inducers of oxidative stress block ciliary neurotrophic factor activation of Jak/STAT signaling in neurons ... Treatment with hydrogen peroxide ( H ( 2 ) O ( 2 ) ) as a generator of ROS inhibited CNTF mediated Jak/STAT signaling in all cultured nerve cells tested, including chick ciliary ganglion neurons, chick neural retina, HMN-1 motor neuron hybrid cells, and SH-SY5Y and BE ( 2 ) -C human neuroblastoma cells
Goureau et al., Dev Neurosci 2004 : Perturbation of STAT and ERK signaling using protein kinase inhibitors and a dominant negative STAT3 mutant demonstrates that both CNTF induced STAT and ERK activation are involved in promoting Muller cell production
Rhee et al., Adv Exp Med Biol 2010 : CNTF/LIF activates Jak-STAT , ERK, and Notch pathways during retinal development
Bonni et al., Science 1997 : Although CNTF stimulated both the Janus kinase-signal transducer and activator of transcription ( JAK-STAT ) and Ras-mitogen activated protein kinase signaling pathways in cortical precursor cells, the JAK-STAT signaling pathway selectively enhanced differentiation of these precursors along a glial lineage