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C1QB — IL8

Text-mined interactions from Literome

Khalkhali-Ellis et al., J Immunol 1999 : C1q containing immune complexes purified from sera of juvenile rheumatoid arthritis patients mediate IL-8 production by human synoviocytes : role of C1q receptors
Xiao et al., Clin Exp Immunol 2001 : These experiments demonstrate that C1q-IC induced production of IL-8 in HUVEC is dependent upon the activation of PTK and MAPK
Groeneveld et al., J Immunol 2005 : Decorin and biglycan strongly inhibited C1q binding to human endothelial cells and U937 cells, and biglycan suppressed C1q induced MCP-1 and IL-8 production by human endothelial cells
Baruah et al., J Leukoc Biol 2006 : C1q increases the phagocytosis of apoptotic cells by DC and the release of interleukin-12 in the presence of TLR4 ligands and apoptotic cells ; PTX3 inhibits both events
Bottazzi et al., J Biol Chem 1997 : The capacity to bind C1q , mediated by the pentraxin domain, is consistent with the view that PTX3, produced in tissues by endothelial cells or macrophages in response to interleukin-1 and tumor necrosis factor, may act as a local regulator of innate immunity