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HSPB1 — IL8

Text-mined interactions from Literome

Santell et al., Biochem J 1992 : Down-regulation of protein kinase C-alpha by prolonged treatment with phorbol esters eliminated the ability of phorbol 12-myristate 13-acetate, dioctanoylglycerol, thrombin and histamine to phosphorylate HSP27 above background levels and deceased interleukin-1 stimulated HSP27 phosphorylation by 60 %
Sur et al., J Invest Dermatol 2008 : Moreover, downregulation of Hsp27 increased the release of the pro-inflammatory cytokine IL-8 from TNF-alpha stimulated and UV-irradiated keratinocytes, and this increase was inhibited by pretreatment with the NF-kappaB inhibitor BAY11-7082
Su et al., Biochim Biophys Acta 2008 (MAP Kinase Signaling System) : We evaluated the role of p38 MAPK, MK2 and HSP27 in regulating the TNF induced expression of ICAM-1 and IL-8 in human lung MVECs
Cuenda et al., FEBS Lett 1995 : We now show that one of these compounds ( SB 203580 ) inhibits RK in vitro ( IC50 = 0.6 microM ), suppresses the activation of MAPKAP kinase-2 and prevents the phosphorylation of heat shock protein (HSP) 27 in response to interleukin-1 , cellular stresses and bacterial endotoxin in vivo