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IKBKB — RAC1
Text-mined interactions from Literome
Cammarano et al., J Biol Chem 2001
:
Whereas
Rac stimulates the activity of the I kappa B kinase
IKK beta , Cdc42 and Rho activate NF kappa B without activating either IKK alpha or IKK beta ... Like Dbl,
Rac activation of
IKK beta is mediated by the serine/threonine kinases NIK but not MEKK
Venkatesan et al., J Mol Cell Cardiol 2010
:
EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via
Rac1 dependent
PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 signaling ... We show for the first time that EMMPRIN stimulates the activation of NF-kappaB, AP-1, CREB, and ATF-2 in cardiomyocytes, and induces IL-18 expression via
Rac1 dependent
PI3K/Akt/IKK/NF-kappaB and MKK7/JNK/AP-1 signaling