Gene interactions and pathways from curated databases and text-mining

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IKBKB — RAC1

Text-mined interactions from Literome

Cammarano et al., J Biol Chem 2001 : Whereas Rac stimulates the activity of the I kappa B kinase IKK beta , Cdc42 and Rho activate NF kappa B without activating either IKK alpha or IKK beta ... Like Dbl, Rac activation of IKK beta is mediated by the serine/threonine kinases NIK but not MEKK
Venkatesan et al., J Mol Cell Cardiol 2010 : EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1 dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 signaling ... We show for the first time that EMMPRIN stimulates the activation of NF-kappaB, AP-1, CREB, and ATF-2 in cardiomyocytes, and induces IL-18 expression via Rac1 dependent PI3K/Akt/IKK/NF-kappaB and MKK7/JNK/AP-1 signaling