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RAC1 — RDX

Text-mined interactions from Literome

Liu et al., J Biol Chem 2005 : Radixin stimulates Rac1 and Ca2+/calmodulin dependent kinase, CaMKII : cross-talk with Galpha13 signaling
Kahsai et al., Biochim Biophys Acta 2010 : Expression of a phosphomimetic ( Thr-564-to-Asp ) mutant of radixin resulted in increased Rac1 activity, membrane protrusion and cell motility in MDCK cells, suggesting that radixin functions `` upstream '' of Rac1, presumably as a scaffolding protein
Adyshev et al., Cell Signal 2011 : Silencing of either all ERM proteins or radixin alone ( but not moesin alone ) reduced S1P induced Rac1 activation and phosphorylation of the downstream Rac1 effector PAK1
Shaw et al., Mol Biol Cell 1998 : An activated allele of RhoA, but not Rac or CDC42Hs, was sufficient to induce apical membrane/actin protrusions and localize radixin or moesin into these structures in both Rat1 and NIH3T3 cells