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EGFR — ICR1

Text-mined interactions from Literome

Modjtahedi et al., Biochem Biophys Res Commun 1996 : We show that one of these mAbs ( ICR62 ) also prevents activation of the EGFR by betacellulin as evidenced by reversal of the effects on the growth of human fibroblasts and the head and neck carcinoma cell line HN5 and by inhibition of receptor phosphorylation in HN5 cells
Modjtahedi et al., Int J Cancer 1998 : Like EGF, we found that both the epiregulin induced growth inhibition of HN5 and MDA-MB468 cells and tyrosine phosphorylation of the 170 kDa EGFR on HN5 cells are reversed in the presence of anti-EGFR MAbs ICR62 and ICR80