Martin et al., Invest Ophthalmol Vis Sci 2004
(Eye Abnormalities...) :
In the HVS, Arf expression in perivascular cells may block their accumulation or repress Vegf expression to promote HVS involution and prevent PHPV
Ikeda et al., Circ Res 2005
(Ischemia) :
Thus, ARF6 is involved in the temporal-spatial organization of caveolae/lipid rafts- and ROS dependent VEGF signaling in ECs as well as in angiogenesis in vivo