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ADIPOQ — PRKAA2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Ouchi et al., J Biol Chem 2004
(Neovascularization, Pathologic) :
Adiponectin promoted the phosphorylation of
AMP activated protein kinase (AMPK) , protein kinase Akt/protein kinase B, and endothelial nitric oxide synthesis ( eNOS ) in HUVECs
Huypens et al., Life Sci 2005
:
Adiponectin mediated stimulation of
AMP activated protein kinase (AMPK) in pancreatic beta cells
Nawrocki et al., J Biol Chem 2006
(Insulin Resistance) :
Adiponectin is
required for the activation of
AMPK upon TZD administration in both liver and muscle
Tang et al., J Immunol 2007
:
Adiponectin increased the kinase activity and phosphorylation of
AMPK and p38
Li et al., Sheng Li Xue Bao 2007
:
Adiponectin activates
AMPK phosphorylation and then promotes ATP generating pathways in heart, including glucose transport, glycolysis, and fatty acid oxidation
Lu et al., Mol Endocrinol 2008
:
Adiponectin increases phosphorylation of
AMP activated protein kinase (AMPK) , a downstream target of adiponectin receptors, and reduces basal and GnRH stimulated LH secretion, acutely
Guillod-Maximin et al., J Endocrinol 2009
:
Adiponectin is able to
increase AMPK phosphorylation in the rat hypothalamus
Kim et al., Mol Endocrinol 2010
(Colonic Neoplasms) :
Adiponectin stimulated
AMP activated protein kinase (AMPK) phosphorylation whereas inhibition of AMPK activity blunted the effect of adiponectin on the proliferation of colon cancer cells
Liu et al., FASEB J 2010
:
Adiponectin activates
AMP activated protein kinase (AMPK) in adipocytes, but the underlying mechanism remains unclear
Liu et al., Biochimie 2012
:
Adiponectin levels are also
stimulated by FOXO1 and
AMP activated protein kinase (AMPK) , and are suppressed by PKA or silencing mediator of retinoid and thyroid hormone receptors ( SMRT )
Shehzad et al., Hormones (Athens) 2012
(Diabetes Mellitus...) :
Adiponectin enhances
AMPK and the PPARa pathway in the liver and skeletal muscle