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SMAD3 — TAS2R13

Text-mined interactions from Literome

Chan et al., Mol Cell Biol 2007 : Upon BMP stimulation, Trb3 dissociates from BMPRII-TD and triggers degradation of Smad ubiquitin regulatory factor 1 ( Smurf1 ), which results in the stabilization of BMP receptor regulated Smads and potentiation of the Smad pathway
Park et al., Mol Cell Biol 2009 : Both Trb3 and phenamil stabilize the expression of SMAD , the critical transcription factor in BMP signaling, by promoting the degradation of SMAD ubiquitin regulatory factor 1
Hua et al., J Cell Sci 2011 (Neoplasm Invasiveness) : Expression of exogenous TRB3 enhanced the transcriptional activity of SMAD3 , whereas knocking down endogenous TRB3 reduced the transcriptional activity of SMAD3 ... Moreover, TRB3-SMAD3 interaction promoted the nuclear localization of SMAD3 because of the interaction of TRB3 with the MH2 domain of SMAD3