Gene interactions and pathways from curated databases and text-mining

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IL1A — SAP130

Text-mined interactions from Literome

Pietrella et al., Infect Immun 2010 (Inflammation) : In particular Sap1, Sap2 , and Sap6 significantly induced interleukin-1ß (IL-1ß) , tumor necrosis factor alpha ( TNF-a ), and IL-6 production
Sarlo et al., Cell Immunol 1985 : The mouse macrophage line P388D1, also could bind SAP and display enhanced IL-1 production in response to SAP
Ku et al., Cytokine 1993 (Carcinoma, Hepatocellular...) : By contrast, gene expression of the major APR of the mouse, serum amyloid P-component (SAP) , a structural homologue of CRP, increased in response to either IL-1 or IL-6 under the same conditions