Gene interactions and pathways from curated databases and text-mining

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BCR — REL

Text-mined interactions from Literome

Kirchner et al., Exp Hematol 2003 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : Mechanisms of Bcr-Abl mediated NF-kappaB/Rel activation ... In this paper we demonstrate activation of NF-kappaB/Rel by Bcr-Abl and for the first time by v-Abl ... Furthermore, we investigated mechanisms of NF-kappaB/Rel induction by Bcr-Abl and v-Abl
Castro et al., J Immunol 2009 : In this study, we demonstrate that BCR signaling induced more long-term c-Rel activation in T2 and mature than in T1 B cells leading to increased expression of anti-apoptotic genes as well as prosurvival BAFF-R and its downstream substrate p100 ( NF-kappaB2 )
Neumann et al., Anticancer Res 1996 (Leukemia, Megakaryoblastic, Acute) : A human myeloid cell line, Mo7, and a daughter cell line expressing the bcr/abl oncogene, Mo7-P210, were used in a comparative study analyzing the effects of p210BCR/ABL expression on tyrosine phosphorylation, specific DNA binding and expression of the proto-oncoprotein c-Rel