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BCR — REL
Text-mined interactions from Literome
Kirchner et al., Exp Hematol 2003
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
Mechanisms of
Bcr-Abl mediated
NF-kappaB/Rel activation ... In this paper we demonstrate
activation of
NF-kappaB/Rel by
Bcr-Abl and for the first time by v-Abl ... Furthermore, we investigated mechanisms of
NF-kappaB/Rel induction by
Bcr-Abl and v-Abl
Castro et al., J Immunol 2009
:
In this study, we demonstrate that
BCR signaling
induced more long-term
c-Rel activation in T2 and mature than in T1 B cells leading to increased expression of anti-apoptotic genes as well as prosurvival BAFF-R and its downstream substrate p100 ( NF-kappaB2 )
Neumann et al., Anticancer Res 1996
(Leukemia, Megakaryoblastic, Acute) :
A human myeloid cell line, Mo7, and a daughter cell line expressing the bcr/abl oncogene, Mo7-P210, were used in a comparative study analyzing the
effects of
p210BCR/ABL expression on tyrosine phosphorylation, specific DNA binding and expression of the proto-oncoprotein
c-Rel