Gene interactions and pathways from curated databases and text-mining

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FAS — LEP

Text-mined interactions from Literome

Dridi et al., Domest Anim Endocrinol 2005 : Despite the decrease of food intake, leptin significantly induced the expression of FAS in chicken liver
Tanaka et al., Int J Mol Med 2008 : Leptin enhanced anti-Fas IgM mediated growth inhibition and DNA fragmentation, but did not enhance the expression of either Fas antigen or Fas ligand
Yamamoto et al., Food Funct 2011 (Body Weight...) : These findings suggest that the regulation of leptin secretion by APE may inhibit FAS activity with subsequent suppression of triglyceride accumulation in the liver and adipose tissues