Gene interactions and pathways from curated databases and text-mining

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PDGFRB — SMC2

Text-mined interactions from Literome

Liu et al., FASEB J 2007 : In summary, these results demonstrate that 5-HT transactivates PDGFRbeta in PASMCs leading to SMC proliferation and migration, and may be an important signaling pathway in the production of PH in vivo
Lamy et al., Carcinogenesis 2008 (Neovascularization, Pathologic) : The inhibitory effect of delphinidin on PDGFR-beta was very rapid and led to the inhibition of PDGF-BB induced activation of extracellular signal regulated kinase ( ERK)-1/2 signaling and of the chemotactic motility of SMC, as well as the differentiation and stabilization of EC and SMC into capillary-like tubular structures in a three-dimensional coculture system
Fukai et al., Arterioscler Thromb Vasc Biol 2009 (Carotid Artery Injuries...) : These results suggest the possibility that syndecan-1 may limit intimal thickening in injured arteries by suppressing SMC activation through inhibition of SMC PDGF-B chain expression and PDGFRbeta activation