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PMPCB — RELA

Text-mined interactions from Literome

Helenius et al., Antioxid Redox Signal 2001 : The up-regulation of constitutive nuclear NF-kappa B binding activity and increased levels of nuclear p52 and p65 proteins might affect the expression of some NF-kappa B target genes in the aging liver
Monaco et al., Proc Natl Acad Sci U S A 2004 (Arteriosclerosis...) : We found that NF-kappa B is activated in these cells and that this activity involves p65, p50, and c-Rel but not p52 or RelB
Iwamoto et al., Tohoku J Exp Med 2005 (Body Weight...) : Supershift assays with specific antibodies revealed that p50, but not p52 , p65, Rel B, or c-Rel, may be involved in the activation of NF-kappaB , though the component primarily responsible for the increase could not be determined
Eisner et al., FEBS Lett 2006 : Supershift analysis revealed that p65 and RelB ( but not p50, p52 or cRel ) were involved in the binding of NFkappaB to DNA
Nadiminty et al., Cancer Res 2010 (Disease Progression...) : Comparison of the relative effects of p52 and p65 (RelA) showed that p52 , but not p65, could activate the AR. Collectively, these findings, together with previous reports that the levels of NF-kappaB2/p52 are elevated in prostate cancer cells and that active NF-kappaB2/p52 promotes prostate cancer cell growth in vitro and in vivo, suggest that NF-kappaB2/p52 may play a critical role in the progression of castration-resistant prostate cancer
Li et al., Nat Immunol 2010 : Because of low expression of the transcription factor RelB in untreated macrophages, high p52 expression repressed basal transcription of both canonical and noncanonical NF-kappaB target genes
Altaf et al., Inflammopharmacology 2013 : Only RelA and c-rel ( p < 0.01 ) were increased by one diamond nanoparticle and p52 and c-rel ( p < 0.01 ) by another nanoparticulate diamond