Gene interactions and pathways from curated databases and text-mining

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IL1A — NPY

Text-mined interactions from Literome

Ferreira et al., J Biol Chem 2010 (Inflammation) : Given the modulatory role of neuropeptide Y (NPY) in the immune system, we investigated the effect of NPY on the production of NO and IL-1ß in microglia ... Moreover, NPY acting through Y ( 1 ) receptor inhibited LPS stimulated release of IL-1ß , inhibiting NO synthesis
Zhou et al., J Neuroimmunol 2013 (MAP Kinase Signaling System) : In the present work, we have evaluated the effects of NPY on the release of TNF-a, IL-1ß , IL-6 and HMGB1 mediators in peritoneal macrophages ... Our results demonstrate for the first time that NPY can directly induce active HMGB1 release and cytoplasmic translocation, while the production of TNF-a, IL-1ß and IL-6 is not affected