Gene interactions and pathways from curated databases and text-mining

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ESR1 — FASLG

Text-mined interactions from Literome

Sapi et al., J Soc Gynecol Investig 2002 (Ovarian Neoplasms) : Furthermore, we showed that the estrogen induced increase in the FasL protein and mRNA levels could be abolished by 4-hydroxytamoxifen, which suggests that the observed increase in FasL expression was mediated by estrogen receptor
Nakamura et al., Cell 2007 (Bone Diseases, Metabolic) : Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts
Krum et al., EMBO J 2008 : We have characterized a cell-type-specific hormone-inducible enhancer located 86 kb downstream of the FasL gene as the target of estrogen receptor-alpha induction of FasL expression in osteoblasts