Gene interactions and pathways from curated databases and text-mining

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PTEN — SPARC

Text-mined interactions from Literome

Thomas et al., Neuro Oncol 2010 (Brain Neoplasms...) : PTEN augments SPARC suppression of proliferation and inhibits SPARC induced migration by suppressing SHC-RAF-ERK and AKT signaling
Bhoopathi et al., PloS one 2012 (Neuroblastoma) : SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT