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BAAT — LEP

Text-mined interactions from Literome

Giacobino et al., Int J Obes Relat Metab Disord 1999 (Obesity) : The effects of PPARgamma agonists and leptin on BAT and muscle UCP3 mRNA expression are also discussed
Rodríguez et al., Pflugers Arch 2002 (Obesity) : The effect of cold exposure, being overweight and their interaction was investigated on the response of uncoupling proteins UCP1, UCP2 and UCP3 and the alpha ( 2 ) /beta ( 3 ) adrenergic receptor ( AR ) balance in brown adipose tissue (BAT) , as well as the involvement of leptin gene expression in white adipose tissues, in control and overweight male rats of the dietary obesity model known as the post-cafeteria model
Masaki et al., Endocrinology 2003 : In peripheral tissue, leptin up-regulated BAT UCP1 mRNA expression and reduced fat depositions in this tissue
Gnanalingham et al., Am J Physiol Endocrinol Metab 2005 : Acute leptin decreased the abundance of UCP2, glucocorticoid receptor, and 11beta-hydroxysteroid dehydrogenase ( 11beta-HSD ) type 1 mRNA and increased 11beta-HSD type 2 mRNA abundance in BAT , a pattern that was reversed with chronic leptin administration, which also diminished lung UCP2 protein abundance
Zhang et al., Am J Physiol Regul Integr Comp Physiol 2007 (Body Weight) : We hypothesized that leptin is necessary for homeostatic restoration of the HF-enhanced caloric intake and may mediate the increase in uncoupling protein-1 (UCP1) in brown adipose tissue (BAT)
Scarpace et al., Am J Physiol 1997 (Obesity) : Leptin increased BAT UCP mRNA levels greater than twofold in both ad libitum fed and food restricted rats
Siegrist-Kaiser et al., J Clin Invest 1997 : The chronic peripheral intravenous administration of leptin in vivo for 4 d resulted in a 1.6-fold increase in the in vivo glucose utilization index of BAT, whereas no significant change was found after intracerebroventricular administration compared with pair fed control rats, compatible with a direct effect of leptin on BAT
Scarpace et al., J Endocrinol 1998 : Leptin increased LPL mRNA by 80 %, UCP1 mRNA twofold, and UCP3 mRNA levels by 62 % in BAT , and increased UCP2 mRNA levels twofold in EWAT ... The present study indicates that leptin increases the gene expression of UCP2 in EWAT and that of UCP1, UCP3 and LPL in BAT , whereas reduced food consumption but not leptin, decreases LPL expression in WAT