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FGF1 — FGF14
Text-mined interactions from Literome
Crumley et al., Oncogene 1991
:
High-affinity binding and
activation of a truncated
FGF receptor by both
aFGF and bFGF
Yamamoto et al., J Biol Chem 2008
:
PDGF-AA induced the expression of the
fibroblast growth factor genes Fgf3 and -7, and PDGF-BB
induced the expression of
Fgf1 , -3, -7, and -10, whereas short interfering RNA for Pdgfa and Pdgfb inhibited the expression of Fgf3, -7, and -10, indicating that PDGFs regulate Fgf gene expression in SMG mesenchyme
Mori et al., PloS one 2013
(Colonic Neoplasms...) :
R50E is defective in inducing ternary complex formation, cell proliferation, and cell migration, and suppresses
FGF signaling
induced by WT
FGF1 ( a dominant negative effect ) in vitro
Relf et al., Cancer Res 1997
(Breast Neoplasms...) :
Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic
fibroblast growth factor , tumor growth factor beta-1, platelet
derived endothelial cell growth factor , placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
Zuber et al., J Cell Physiol 1997
:
Cysteine-rich
FGF receptor
regulates intracellular
FGF-1 and FGF-2 levels
Guillonneau et al., Growth Factors 1998
:
In addition,
FGF2 stimulated release of endogenous
FGF1 is associated with reduced apoptosis in RPE cells ... In addition,
FGF2 stimulated the production and release of phosphorylated
FGF1 by RPE cells
Klingenberg et al., J Biol Chem 1998
:
The
aFGF ( K132E ) mutant binds to and
activates fibroblast growth factor receptors equally strongly as the wild-type, but it is a poor mitogen