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CASP3 — CDH1
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Jamal et al., J Clin Invest 2002
(Melanoma) :
Downregulation of
E-cadherin by ET-1/ET ( B )
involves the downstream activation of
caspase-8 but not of distal, executioner caspases, and does not lead to apoptosis
Keller et al., Biochem Biophys Res Commun 2003
(Breast Neoplasms) :
Cleavage of
E-cadherin and deposition of the C-terminal fragment into the cytoplasm are
inhibited by the
caspase inhibitor DEVD-CHO
Hung et al., Exp Dermatol 2006
:
Cleavage of beta- and gamma-catenin was fully abolished by caspase-3 and caspase-8 inhibitors, whereas cleavage of
E-cadherin was
inhibited by neither
caspase nor metalloproteinase inhibitors
Sone et al., Genes Cells 2008
:
Although MDCK cells transfected with GFP fused wild-type hScrib showed loss of E-cadherin expression and shrinkage of cytoplasm by UV irradiation, cells transfected with hScrib with Ala substitution of Asp-504 showed resistance to
caspase dependent cleavage of hScrib and intact expression of
E-cadherin
Obara et al., J Vet Med Sci 2010
(Mycoplasma Infections...) :
Nitric oxide causes anoikis through attenuation of
E-cadherin and
activation of
caspase-3 in human gastric carcinoma AZ-521 cells infected with Mycoplasma hyorhinis ... Our results indicate that NO causes anoikis throughout attenuation of
E-cadherin and
activation of
caspase-3 in human gastric carcinoma cell line AZ-521 cells infected with M. hyorhinis