Gene interactions and pathways from curated databases and text-mining

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CXCL12 — IL32

Text-mined interactions from Literome

Damås et al., Circulation 2002 (Angina, Unstable) : In vitro, SDF-1alpha ( 500 ng/mL ) reduced both unstimulated and endotoxin/mitogen stimulated mRNA and protein levels of monocyte chemoattractant protein-1, interleukin-8 , matrix metalloproteinase-9, and tissue factor while increasing tissue inhibitor of metalloproteinases-1 in PBMC from patients with unstable angina
Heinhuis et al., Ann Rheum Dis 2011 (Arthritis, Rheumatoid) : TNFa stimulation of FLS after silencing IL-32? resulted in diminished IL-6 and CXCL8 production, whereas IL-32? overexpression resulted in enhanced IL-6 and CXCL8 levels ... Remarkably, the mechanism through which IL-32? overexpression induced TNFa, IL-1ß and CXCL8 was by counteracting messenger RNA decay