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ARSA — TGFB1
Text-mined interactions from Literome
Koelink et al., Cancer Lett 2010
(Colorectal Neoplasms) :
5-ASA inhibited
TGF-beta1 signalling in HCT116 cells and colonic fibroblasts, as judged by a TGF-beta-specific reporter gene assay, plasminogen activator inhibitor-1 mRNA and protein levels, fibroblast trans-differentiation, Smad3 phosphorylation and nuclear translocation
Redondo et al., PloS one 2010
(MAP Kinase Signaling System) :
ASA ( 2 mM )
induced TGF-beta1 secretion ; however it was unable to induce Smad activation