Gene interactions and pathways from curated databases and text-mining

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AGTR2 — EGFR

Text-mined interactions from Literome

Fujiyama et al., Circ Res 2001 : AT(2) inhibited AT(1) mediated Ang2 expression and phosphorylation of EGFR
Shibasaki et al., Hypertension 2001 : Angiotensin II type 2 receptor inhibits epidermal growth factor receptor transactivation by increasing association of SHP-1 tyrosine phosphatase ... AT(2) inhibited AT(1) mediated EGFR tyrosine phosphorylation by 63 % ... Stable overexpression of SHP-1-dominant negative mutant completely abolished AT(2) mediated inhibition of EGFR and ERK activation