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ADCYAP1 — BDNF

Text-mined interactions from Literome

Frechilla et al., Neuroreport 2001 : BDNF mediates the neuroprotective effect of PACAP-38 on rat cortical neurons ... In both cellular injury conditions, the diminished BDNF expression was significantly prevented by PACAP
Kidane et al., Endocrinology 2008 : Finally, an in vitro study demonstrates that PACAP stimulates the expression of BDNF transcript IV
Pellegri et al., Eur J Neurosci 1998 : In primary cultures of cortical neurones, induction of BDNF mRNA by VIP and PACAP is completely inhibited by the N-methyl-D-aspartate ( NMDA ) receptor antagonists MK-801 and AP5, therefore indicating that VIP and PACAP do not stimulate BDNF expression directly but rather by potentiating the effect of glutamate tonically released by neurones and acting at NMDA receptors