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NOS2 — VIP
Text-mined interactions from Literome
Dick et al., Eur J Pharmacol 2000
:
The isolation procedure of the smooth muscle cells might induce
iNOS that can be
activated by
VIP
Foster et al., J Interferon Cytokine Res 2005
:
However, although the
effect of
VIP on
inducible nitric oxide synthase (iNOS) was less clear, N-monoethyl arginine ( NEMA ) ( an iNOS inhibitor ) did not rescue S. typhimurium from IFN- gamma induced death, in accordance with previous reports that suggest that iNOS is not an important Salmonella killing pathway in macrophages within the first 24 h. VIP is a potent inhibitor of inflammatory pathways that lead to significant pathologic conditions
Mourad et al., Am J Physiol Gastrointest Liver Physiol 2006
(Colitis...) :
The effects of 1 ) tetrodotoxin ( TTX ), 2 ) benzylalkonium chloride ( BAC ), 3 ) capsaicin, 4 )
vasoactive intestinal polypeptide (VIP) antagonism, 5 )
nitric oxide ( NO ) synthase ( NOS )
inhibition , and 6 ) 5-hydroxytryptamine type 3 and 4 ( 5-HT(3) and 5-HT(4) ) receptor antagonism on the changes in fluid movement were investigated
Sabbatini et al., Eur J Pharmacol 2007
(Proteinuria) :
However, CNP response was unaltered by cholecystokinin and
vasoactive intestinal peptide receptor blockade or by
nitric oxide synthase inhibition
Amato et al., Am J Physiol Gastrointest Liver Physiol 2010
:
GLP-2 inhibitory effect was not affected by N ( ? ) -nitro-l-arginine methyl ester ( a
nitric oxide synthase inhibitor ), apamin ( a blocker of small conductance Ca ( 2+ ) -dependent K ( + ) channels ), or [ Lys1,Pro2,5,Arg3,4,Tyr6 ]
VIP ( 7-28 ) ( a VIP receptor antagonist ), but it was prevented by atropine or pertussis toxin ( PTX ), a G ( i/o ) protein inhibitor
González et al., J Cereb Blood Flow Metab 1997
:
Neuronal
nitric oxide synthase activation by
vasoactive intestinal peptide in bovine cerebral arteries