Gene interactions and pathways from curated databases and text-mining

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AGT — ANG

Text-mined interactions from Literome

Hu et al., Arterioscler Thromb Vasc Biol 2000 : We previously demonstrated that homogeneous cultures of vascular smooth muscle cells ( VSMCs ) from spontaneously hypertensive rats produce angiotensin II (Ang II) in response to increases in the levels of angiotensinogen , cathepsin D, and angiotensin converting enzyme (ACE)
Wong et al., Mol Cell Endocrinol 2007 : In the present study, we have cloned the angiotensinogen for silver sea bream ( Sparus sarba ) and investigated the role of Ang II on angiotensinogen expression ... The effect of Ang II stimulation on angiotensinogen expression is more potent in fish than that in mammals
Nakamura et al., Life Sci 1990 : The results suggest that the angiotensinogen response to ANG II was not dependent on adrenal glucocorticoid
Rusai et al., Transplantation 2011 : In aliskiren treated animals reduced serum Ang II and Ang ( 1-7 ) levels were detected , whereas the level of urine angiotensinogen was unchanged
Coezy et al., Am J Physiol 1989 (Hematoma) : The aim of this study was to examine in Hep G2, a human hepatoma derived cell line, the presence of angiotensin II (ANG II) receptors and the effect of ANG II and its analogues on angiotensinogen production ... Results of these studies show that the Hep G2 cell possesses specific ANG II receptors and that [ Sar1 ] ANG II induces a dose dependent inhibition of angiotensinogen production in this system
Klett et al., Clin Exp Hypertens A 1987 : The effect of angiotensin II (ANG II) on the secretion of angiotensinogen was studied in isolated rat hepatocytes, obtained by the collagenase perfusion technique and Percoll-density gradient centrifugation, and in the isolated perfused rat liver ... In the isolated perfused liver, ANG II induced a similar increase of angiotensinogen secretion, without affecting albumin and total protein secretion rates
Müller et al., Basic Res Cardiol 1998 (Hypertension, Renovascular) : Taken together, these results demonstrate ( 1 ) the cleavage of local angiotensinogen to ANG I within the vascular wall by renin, ( 2 ) renin uptake from the circulation to evoke that local effect, and ( 3 ) a potential regulatory effect by vascular tissue ACE on ANG II production in the vessel wall