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FOS — MAP3K5

Text-mined interactions from Literome

Jibiki et al., Am J Respir Crit Care Med 2003 (Asthma...) : In the present study, to clarify this issue we examined the effect of NO in inducing activator protein-1 (AP-1) activation in human bronchial epithelial cells ( BEC ) and a role of apoptosis signal regulating kinase1 ( ASK1 ), an upstream kinase kinase of c-Jun-NH2-terminal kinase (JNK) and p38 mitogen activated protein kinase ( MAPK ) in NO-mediated AP-1 activation
Kumasawa et al., Eur J Pharmacol 2005 : We examined the effect LTD ( 4 ) on AP-1 activation in human airway smooth muscle cells and analyzed a role of apoptosis signal regulating kinase1 ( ASK1 ), an upstream kinase kinase of c-Jun-NH ( 2 ) -terminal kinase ( JNK ) and p38 mitogen activated protein kinase ( MAPK ) in LTD ( 4 ) -induced AP-1 activation to clarify the signaling molecule regulating AP-1 activation
Roy et al., Cardiovasc Res 2010 (Disease Models, Animal...) : Knockdown of Fra-2 significantly blunted O ( 2 ) -induced expression of TGFbeta1 as well as TGFbeta3 in CF. Knockdown of Ask-1 blunted hyperoxia induced Fra-2 gene expression and nuclear localization in CF. Collectively, these observations point towards a central role of Ask-1 and Fra-2 in O ( 2 ) -inducible AP-1 activation and induction of TGFbeta
Jin et al., Dev Biol 2013 : Second, MAP3K1 potentiated AP-2a expression and SRF and AP-1 activity, but its target genes were enriched for binding motifs of AP-2a and SRF, and not AP-1, suggesting the existence of novel MAP3K1-AP-2a/SRF modules in gene regulation