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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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MAP2K5 — RELA

Text-mined interactions from Literome

Pearson et al., J Biol Chem 2001 (Cell Transformation, Neoplastic) : Consistent with results from our focus-formation assays, constitutively active variants of MEK5 and MEK1 synergize to activate NF-kappaB, and MEK5 and ERK5 are required for activation of NF-kappaB by RafBXB
Ludwig et al., Cancer Res 2001 (Carcinoma, Medullary...) : RET induced NF-kappaB and IKKbeta activity requires Ras function but does neither involve the classical mitogen activated protein kinase kinase/extracellular signal regulated kinase nor the phosphoinositide 3-kinase/Akt pathways
Chen et al., J Biol Chem 2004 (Crohn Disease) : In this study, we determined that mitogen activated protein kinase kinase transforming growth factor ( TGF)-beta activated kinase 1 (TAK1 ) interacts with Nod2 and is required for Nod2 mediated NF-kappaB activation
Ghosh et al., J Biol Chem 2005 (MAP Kinase Signaling System...) : MBP-1 expression also modulates MEK5 mediated activation of NF-kappaB