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ANGPT2 — HMOX1

Text-mined interactions from Literome

Ishizaka et al., Hypertension 2002 (Hypertension) : Immunoblot analysis demonstrated that Ang II increased renal expression of HSP70 and HSP25, as well as HO-1 , but that expression of alphaB-crystallin was unaffected by this treatment
Quan et al., Kidney Int 2004 : The effects of HO-1 transduction on HO-1 expression, HO activity and the response to Ang II with respect to cyclooxygenase-2 (COX-2) up-regulation and oxidative injury [ growth stimulating hormone ( GSH ) levels and cell death ] were determined ... Moreover, Ang II-mediated DNA degradation was completely blocked by the site-specific expression of human HO-1 gene
Dulak et al., Endothelium : journal of endothelial cell research 2005 : Atorvastatin stimulated the expression of angiopoietin (Ang)-2 and moderately enhanced the expression of endothelial nitric oxide synthase (eNOS), whereas heme oxygenase-1 (HO-1) was not significantly affected
Foo et al., J Cell Physiol 2006 (Hypertrophy) : Our findings demonstrate that Ang II ( 100 nM, 24 h ) alone upregulates HO-1 expression and induces both myocyte hypertrophy and apoptosis, assessed by measuring terminal deoxynucleotidyltransferase dUTP nick-end labelling ( TUNEL ) staining, caspase-3 activity and mitochondrial membrane potential
Nath et al., Am J Physiol Regul Integr Comp Physiol 2010 : ANG II causes renal injury through hemodynamic and other effects, and pressor doses of ANG II induce heme oxygenase-1 (HO-1) as a protective response