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IL6 — NOD1
Text-mined interactions from Literome
Masumoto et al., J Exp Med 2006
:
Nod1 stimulation did not
induce TNFalpha,
interleukin 12, and interferon gamma, suggesting that the primary role of Nod1 is to induce the recruitment of immune cells
Cho et al., Microb Pathog 2010
:
These changes in IL-1beta,
IL-6 , IL-8, and ICAM-1
induced by
NOD1 knockdown were reversed as the result of IL-32 treatment
Geddes et al., Nat Med 2011
(Colitis...) :
Enteric innate T helper type 17 ( iT ( H ) 17 ) responses occurred principally in the cecum, were
dependent on the
Nod-like receptors Nod1 and Nod2, required
IL-6 induction and were associated with a decrease in mucosal CD103 ( + ) dendritic cells
Zhao et al., Am J Physiol Endocrinol Metab 2011
(Insulin Resistance...) :
Stimulation of
NOD1 with a synthetic ligand Tri-DAP
induces proinflammatory chemokine MCP-1, RANTES, and cytokine TNF-a and MIP-2 ( human IL-8 homolog ) and
IL-6 mRNA expression in 3T3-L1 adipocytes in a time- and dose dependent manner
de Jong et al., PLoS Pathog 2012
(Salmonella Infections...) :
The interaction of Salmonella pathogen associated molecular patterns ( PAMPs ) with Toll-like receptors ( TLRs ) and
NOD-like receptors ( NLRs ) leads to inflammasome formation, activation, and recruitment of neutrophils and macrophages and the production of pro-inflammatory cytokines, most notably
interleukin (IL)-6 , IL-1ß, tumor necrosis factor (TNF)-a, and interferon-gamma (IFN)-?