Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Zingarelli et al., FASEB J 2002 (Myocardial Infarction...) : These events were preceded by degradation of inhibitor kappaBalpha ( IkappaBalpha ), activation of IkappaB kinase complex (IKK) and c-Jun-NH2-terminal kinase (JNK), and subsequently activation of nuclear factor-kappaB (NF-kappaB) and activator protein 1 (AP-1) as early as 15 min after reperfusion
Chang et al., Exp Cell Res 2002 : This suggests that IL-8 induction by LTbetaR is via TRAFs elicited signaling pathways, including NIK/IKK dependent NF-kappaB activation and ASK/MKK/JNK dependent AP-1 activation
Tsutsumi et al., Virology 2002 : In addition, the activities of c-Jun N-terminal kinase and activator protein-1 (AP-1) , downstream effectors, were enhanced , while IkappaB kinase or nuclear factor-kappaB activities were not enhanced
Qu et al., Blood 2004 : The antigen induced tyrosine phosphorylation of FcepsilonRI, Syk, phospholipase C-gamma (PLC-gamma), activation of c-Jun N-terminal kinase (JNK) , extracellular signal regulated kinase ( ERK ), inhibitor of nuclear factor kappaB kinase ( IKK ), and Ca++ influx were all suppressed in the cells overexpressing Cbl-b in the lipid raft
Zingarelli et al., J Immunol 2003 (Bacteremia...) : These events were preceded by degradation of inhibitor kappaBalpha ( IkappaBalpha ), activation of IkappaB kinase complex , and c-Jun NH ( 2 ) -terminal kinase and, subsequently, activation of NF-kappaB and AP-1 in the lung
Krappmann et al., Mol Cell Biol 2004 : The IkappaB kinase complex and NF-kappaB act as master regulators of lipopolysaccharide induced gene expression and control subordinate activation of AP-1
Aneja et al., Mol Med 2004 (Myocardial Reperfusion Injury) : These events were associated with cytosol degradation of inhibitor kappaB-alpha, activation of IkappaB kinase , phosphorylation of c-Jun, and subsequent activation of nuclear factor-kappaB and activator protein-1 in the infarcted heart
Song et al., Exp Cell Res 2008 (MAP Kinase Signaling System) : Therefore, we concluded that both IKKalpha and IKKbeta can mediate arsenite induced AP-1 transactivation through NF-kappaB activity independent manner