Gene interactions and pathways from curated databases and text-mining

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CASP3 — NPY6R

Text-mined interactions from Literome

Gendron et al., J Biol Chem 2003 : Furthermore, we found that activation of protein phosphatase 2A (PP2A) by Coll I was required for both Coll I-mediated activation of Erk, and inhibition of Fas induced caspase-8 activation and apoptosis
Melendez et al., J Biol Chem 2004 : Multiple apoptotic signaling cascades are recruited by RAFTK as demonstrated by prevention of apoptosis using caspase-3 inhibitor IV ( caspase-3 specific inhibitor ), PP2 ( Src-specific kinase inhibitor ), or Csk ( cellular negative regulator for Src ), as well as dominant negative constructs for p38beta or MKP-1
Dahmani et al., Anesth Analg 2007 : The expression of cleaved caspase 3 was increased by lidocaine, but not bupivacaine, at millimolar concentrations and was blocked by PP2